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  5 out of 5 stars | Average rating from 5 reviews

DHEA: DHEA (dehydroepiandrosterone) is an endogenous hormone (made in the human body), and secreted by the adrenal gland. DHEA serves as precursor to male and female sex hormones (androgens and estrogens). DHEA levels in the body begin to decrease after age 30, and are reported to be low in some people with anorexia, end-stage kidney disease, type 2 diabetes (non-insulin dependent diabetes), AIDS, adrenal insufficiency, and in the critically ill. DHEA levels may also be depleted by a number of drugs, including insulin, corticosteroids, opiates, and danazol.
Source: http://www.mayoclinic.com/

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Reviews from the Community

5 out of 5 |   Reviewed on

DHEA Effective in Treating DOR

DHEA is a relatively recent but very effective development in female infertility, used primarily in women with diminished ovarian reserve (DOR) to improve chances of successful pregnancy. DOR occurs either due to premature ovarian aging (POA) in younger women, or as a natural consequence of female aging.

After years of research and many published studies, physicians at…
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DHEA is a relatively recent but very effective development in female infertility, used primarily in women with diminished ovarian reserve (DOR) to improve chances of successful pregnancy. DOR occurs either due to premature ovarian aging (POA) in younger women, or as a natural consequence of female aging.

After years of research and many published studies, physicians at the Center for Human Reproduction (CHR) and many colleagues around the world are now successfully utilizing DHEA in women with DOR. Our studies have demonstrated that in such patients DHEA supplementation significantly improves IVF pregnancy rates and reduces miscarriage rates. Better IVF pregnancy rates and fewer miscarriages are the consequence of better egg and embryo quality.

Egg and embryo quality is improved because DHEA supplementation raises the levels of male hormones in ovaries, especially the hormone testosterone. We now understand that normal testosterone levels are crucial for the early stages of follicle maturation. As CHR investigators also demonstrated and reported in a number of publications, male hormone levels in women with DOR are usually abnormally low.

All of this represents a remarkable departure from the traditional fertility treatments of the past 50 years, which only focused on the last 2 weeks of egg development. By treating early stages of follicle maturation, CHR researchers have really advanced fertility treatments into a completely new direction. Moreover, by treating earlier stages of follicle maturation, we can exert more influence on egg quality than starting at late stages. As a consequence, the CHR team was able to demonstrate that even women with undetectable levels of anti-Müllerian hormone (AMH), suggestive of very severe DOR, can still expect respectable IVF pregnancy chances after DHEA supplementation.

As the efficacy of DHEA supplementation appears to hinge upon a woman’s ability to convert DHEA to other androgens (primarily testosterone), we carefully monitor testosterone levels of our patients on DHEA supplementation. To be maximally successful, DHEA supplementation also needs to be accompanied by an individualized IVF protocol that best suits the patient. Consultation with a knowledgeable reproductive endocrinologist is, therefore, always recommended before initiating DHEA supplementation.

The website for Fertinatal, a DHEA supplement, has additional information: http://www.fertinatal.com/
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(100% people found this review helpful)

5 out of 5 |   Reviewed on

Amazing Results

I found out two years ago that I had a low ovarian reserve. After long days and nights of stressing about the situation, I dediced that I wanted to take matters into my own hands, and opt for treatment. I've never been so happy with a decision. After treatment, my tests showed that I had enhanced follicle and egg development,…
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I found out two years ago that I had a low ovarian reserve. After long days and nights of stressing about the situation, I dediced that I wanted to take matters into my own hands, and opt for treatment. I've never been so happy with a decision. After treatment, my tests showed that I had enhanced follicle and egg development, and new potential increase in the number of follicles in my ovaries. Things are looking up, and I'm hoping to continue treatment until I can get pregnant!
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(0% people found this review helpful)

5 out of 5 |   Reviewed on

Miraculous

I had been told so many times that women with low ovarian reserves are less likely to fall pregnant either naturally or after fertility treatment, and that my chances were slim. I knew my body wouldn't respond well to the drugs used to stimulate my ovaries during IVF treatment and that I coudn't produce enough eggs. After DHEA treatment, this…
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I had been told so many times that women with low ovarian reserves are less likely to fall pregnant either naturally or after fertility treatment, and that my chances were slim. I knew my body wouldn't respond well to the drugs used to stimulate my ovaries during IVF treatment and that I coudn't produce enough eggs. After DHEA treatment, this changed. The number and quality of my embryoes dramatically increased after having it. I'm now pregnant wtih my first child!
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(0% people found this review helpful)

5 out of 5 |   Reviewed on

42 and Pregnant

After turning 42, I was told I had DOR, or diminished ovarian reserve. I had one child when I was 38, and trying desperately since then to have another. I love being a mother, it's the most fulfilling aspect of my life. Having lots of kids was something I wanted ever since I could remember. I knew I had little…
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After turning 42, I was told I had DOR, or diminished ovarian reserve. I had one child when I was 38, and trying desperately since then to have another. I love being a mother, it's the most fulfilling aspect of my life. Having lots of kids was something I wanted ever since I could remember. I knew I had little chances of getting pregnant with my condition, so I decided to try DHEA. I can happily report that I am now pregnant with my second child, and couldn't be more estatic.
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(0% people found this review helpful)

5 out of 5 |   Reviewed on

Incredible

To any woman who has ever been told: you'll never have a baby, you'll never be a mom, maybe you should look into adoption centers, or that you're only choice is egg donation, I stand here, against all odds, to tell you that this treatment can change everything for you. I was told when I was in high school that…
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To any woman who has ever been told: you'll never have a baby, you'll never be a mom, maybe you should look into adoption centers, or that you're only choice is egg donation, I stand here, against all odds, to tell you that this treatment can change everything for you. I was told when I was in high school that I had DOR and that it was unlikely I could ever hold my own baby in my arms. I am now fertile because of this treatment. DHEA supplementation has, worldwide, demonstrated remarkable results. I encourage you to look into it.
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(0% people found this review helpful)
 

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